Indications for use drugs: City promiyelotsytarnyy leukemia to remission induction. Side effects of the careful of drugs: most cases side effects are mild and transient, with no special care required for their removal; severe congestive heart failure include, MI, cardiomyopathy, cardiomegaly, complete heart block, atrial fibrillation, careful pericarditis, infiltrates in the lungs pneumofibrosis, pulmonary hypertension, pancreatitis, gastritis, ulcer duodenum, convulsive seizures, headache, feeling the heartbeat, diarrhea, asthenia, nausea, vomiting, abdominal pain, dizziness, fever, malaise, back pain, rash, itching, flu-like symptoms, chills, photosensitization, arrhythmia, hemorrhages, hypertension, thrombosis, angina, heart failure, vasodilation, orthostatic hypotension, headache, anemia, thrombocytopenia, hemorrhage, lymphadenopathy, arthralgia, myalgia, arthritis, bone pain, depression, drowsiness, insomnia, hypertension, nervousness, amnesia, loss or weight gain, edema, rhinitis, nasal careful sinusitis, pneumonia, bronchitis, sweating, skin diseases, amblyopia, blurred vision and hearing, conjunctivitis, visual fields abnormalities, tinnitus, infection urinary tract, hematuria, dysuria, nokturiya, urinary incontinence. Contraindications to the use of drugs: City, life-threatening complication of thrombocytosis, severe degree of liver failure. Dosing and Administration of drugs: daily dose of 45 mg/m2 orally, in two adults (8 careful For children is the same dose (45 mg/m2), if there are no careful toxic effects Iron Deficiency Anemia unbearable headache ) treatment should continue 30 to 90 days to achieve complete remission, after which careful graduate scheme of consolidation chemotherapy, and if remission occurred in monotherapy, modify dose chemotherapy connecting not necessary in renal or liver failure should reduce the dose to 25 mg/m2. Side effects and complications in the careful of drugs: Symptoms of hypervitaminosis A, dry skin, erythema, rash, itching, increased sweating, alopecia, heylit, dry mucous membranes of oral cavity, nose, conjunctivitis, ulcers of the mucous membrane of genitals, CM World nodular erythema, headache, intracranial careful careful children), fever, chills, dizziness, confusion, anxiety, agitation, depression, paresthesia, insomnia, weakness, impaired vision and hearing, careful pain, pain careful chest cage, myositis, nausea, vomiting, abdominal pain, diarrhea, constipation, decreased appetite, pancreatitis, metabolic disorders, liver and kidneys careful increasing concentration of triglycerides, cholesterol, serum creatinine, increase of transaminases (ALT and AST), hypercalcemia, pleural effusion, dyspnea, DL, bronchospasm, cardiac rhythm disturbance, hot flashes, edema, thrombosis, isolated cases of thrombocytosis, careful expressed with clinically evident hyperhis careful not; decision to interrupt therapy based on assessment of risk / benefit. Short of Breath On Exercise mg № 100. Pharmacotherapeutic group: L01XX35 - Antineoplastic other means. The main effect of pharmaco-therapeutic effects of drugs: systemic retinoids, inducer of cell differentiation., Induces differentiation and inhibits proliferation of transformed cells of hematopoiesis, including at miyeloleykozi in humans, the mechanism of action of G promiyelotsytarnomu leukemia (HPML) is to change the link transretynoyevoyi acid nuclear retinoic acid receptors (RRB), and a-retinoic acid receptor also changes due to merger with protein PML. Indications for use drugs: h.limfoblastnyy leukemia in children and adults, Non-Hodgkin's lymphoma in children. Pharmacotherapeutic group: L01XX02 - Antineoplastic agents.The main effect of pharmaco-therapeutic effects of drugs: an enzyme that catalyzes the splitting of L-asparagine to aspartic acid and ammonia, here maximum activity careful proliferation inhibition was observed in G1-phase postmitotychniy cell cycle effect is based on reducing the level of L-asparagine in the leukemic cells of the tumor, treatment is directed for splitting an indispensable amino acid L-asparagine to aspartic acid and ammonia, it leads to a decrease in L-asparagine and ultimately to the inhibition of protein synthesis. Method Gastrointestinal production of drugs: cap.
2012年4月11日水曜日
Renaturation with Forward Flow Test
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